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ISRIB (trans-isomer)

CAT: 0931-T6183-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6183-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1597403-47-8
Target
Autophagy, Apoptosis, PERK
Related Pathways
Autophagy, Apoptosis
Purity
0.9927
Bioactivity
ISRIB (trans-isomer) is a potent inhibitor of PERK (IC50=5 nM) that restores protein translation and prevents SG formation in the presence of P-eIF2α.
Smiles
Clc1ccc(OCC(=O)N[C@H]2CC[C@@H](CC2)NC(=O)COc2ccc(Cl)cc2)cc1
Molecular Formula
C22H24Cl2N2O4
Molecular Weight
451.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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