Phlorizin

CAT: 0013-GTR19171669-01Size: 200 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19171669-01Size:200 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Phlorizin is a natural, non-selective SGLT inhibitor isolated from apple, exhibiting inhibitory activity against hSGLT1 (Ki=300 nM) and hSGLT2 (Ki=39 nM) . It is widely used in research to study glucose transport mechanisms in renal physiology and diabetes, both in vitro and in animal models.

CAS Number

60-81-1

Product Name Alternative

Inhibit, NSC 2833, Na+/K+ ATPase, NSC2833, NSC-2833, Floridzin, Inhibitor, hSGLT1, hSGLT2, Sodium potassium pump, Sodium-dependent glucose cotransporters, Phlorizin, Phloridzin, SGLT

Field of Research

Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

DMSO:118 mg/mL (270.39 mM) ; Ethanol:43.6 mg/mL (99.91 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.17 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

C (CCC1=CC=C (O) C=C1) (=O) C2=C (O[C@@H]3O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]3O) C=C (O) C=C2O

Molecular Formula

C21H24O10

Molecular Weight

436.41

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Phloridzin

phloridzin has been reported in Malus, Lithocarpus litseifolius, and other organisms with data available.

CAS Number	60-81-1
PubChem CID	45933907
IUPAC Name	1-[2,4-dihydroxy-6-[(2S,4R,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one
Molecular Formula	C21H24O10
Molecular Weight	436.4
XLogP	1.2
Topological Polar Surface Area	177
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	7
Heavy Atom Count	31
Formal Charge	0
Complexity	581

SMILES

C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O[C@H]3C([C@@H]([C@@H](C(O3)CO)O)O)O)O)O)O

InChI

InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16?,18-,19-,20?,21-/m1/s1

InChIKey

IOUVKUPGCMBWBT-HXBJIUPGSA-N

Chemical Structure

2D Structure

CAS: 60-81-1

CID: 45933907

Formula: C21H24O10

MW: 436.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	436.4
XLogP3	1.2
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	7
Exact Mass	436.13694696
Monoisotopic Mass	436.13694696
Topological Polar Surface Area	177 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	581
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
GTR19153557	Phloridzin
GTR19158725-01	Phloretin
GTR19171646-01	Phloretin
GTR19180047	Phlorin
GTR19228759-01	Phloretin 3',5'-Di-C-glucoside
GTR19237151-01	Phloretin 3,5-Di-C-glucoside
GTR19228510-01	4'-O- (6-O-Feruloylglucopyranosyl) phloretin

Alternative Products

Catalog	Name
HY-N0143-01	Phlorizin
T2S2003-01	Phlorizin dihydrate
HY-N0143A-01	Phlorizin (dihydrate)
E1KS2343	Phlorizin (Phloridzin)
JH303566	Phlorizin chalcone
A10724-5000	Phlorizin 5g
A10724-1000	Phlorizin 1g
A10724-500	Phlorizin 500mg
HY-N0143R-01	Phlorizin (Standard)

Phlorizin

Chemical Information

Related Products

Alternative Products

Popular Products