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BML-284

CAT: 0013-GTR19171413-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171413-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BML-284 (Wnt agonist 1) is a cell-permeable, selective small molecule that potently activates Wnt/β-catenin signaling. It is widely used in vitro to study stem cell biology, tissue regeneration, and oncogenesis, and has been applied in vivo within bone and cartilage research models.
CAS Number
853220-52-7
Product Name Alternative
Betacatenin, beta-catenin, AGS, BML 284, BML284, BML-284, bcatenin, cardiac defect, E-cadherin, Inhibitor, malformed phenotype, inhibit, N-cadherin, MNK45, Wnt agonist 1, Wnt, Wnt/betacatenin, Wnt/b-catenin, Wnt/β-catenin, TCF, βcatenin
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
99.66% (May vary between batches)
Solubility
DMSO:255 mg/mL (727.8 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.71 mM)
Smiles
COc1cccc (c1) -c1cc (NCc2ccc3OCOc3c2) nc (N) n1
Molecular Formula
C19H18N4O3
Molecular Weight
350.37
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine

N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine is a member of pyrimidines.

CAS Number853220-52-7
PubChem CID11210285
IUPAC Name4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine
Molecular FormulaC19H18N4O3
Molecular Weight350.4
XLogP3.1
Topological Polar Surface Area91.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count26
Formal Charge0
Complexity455
SMILES
COC1=CC=CC(=C1)C2=CC(=NC(=N2)N)NCC3=CC4=C(C=C3)OCO4
InChI
InChI=1S/C19H18N4O3/c1-24-14-4-2-3-13(8-14)15-9-18(23-19(20)22-15)21-10-12-5-6-16-17(7-12)26-11-25-16/h2-9H,10-11H2,1H3,(H3,20,21,22,23)
InChIKey
FABQUVYDAXWUQP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine
CAS: 853220-52-7
CID: 11210285
Formula: C19H18N4O3
MW: 350.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight350.4
XLogP33.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass350.13789045
Monoisotopic Mass350.13789045
Topological Polar Surface Area91.5 Ų
Heavy Atom Count26
Formal Charge0
Complexity455
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS131522BML-284 (BML 284; BML284)
HY-19987-01BML-284
MBS5764981BML-284 HCL
BUP12155-01BML-284 hydrochloride
HY-19987R-01BML-284 (Standard)
HY-19987ABML-284 (hydrochloride)
S8178-01BML-284 (Wnt agonist 1)

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