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AV-412 free base

CAT: 0013-GTR19178861Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19178861Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AV-412 free base is a potent and selective small molecule inhibitor targeting EGFR and its common mutants, including T790M and L858R, with IC50 values in the low nanomolar range. It serves as a valuable research tool for investigating EGFR-driven oncogenesis in both cellular and animal models of non-small cell lung cancer and other malignancies.
CAS Number
451492-95-8
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
CN1CCN (CC1) C (C) (C) C#Cc1cc2ncnc (Nc3ccc (F) c (Cl) c3) c2cc1NC (=O) C=C
Molecular Formula
C27H28ClFN6O
Molecular Weight
507
Storage Conditions
-20°C
Notes
For research use only.

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