Products for Research Use Only
RegisterLogin

PF 477736

CAT: 0013-GTR19171814-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19171814-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PF-00477736 is a potent and selective ATP-competitive inhibitor of Chk1 (Ki=0.49 nM) with additional activity against kinases including Aurora-A and FGFR3. It is widely used in vitro and in vivo to study DNA damage response, cell cycle checkpoint control, and as a chemosensitizing agent in cancer research.
CAS Number
952021-60-2
Product Name Alternative
FLT3, FGFR, cFms, c-Fms, Checkpoint Kinase (Chk), Chk1, Chk2, CDK, cRET, Aurora Kinase, AuroraKinase, VEGFR, VEGFR2, PF-736, PF 00477736, PF-736, PF00477736, PF477736, PF-477736, PF00477736, PF-00477736, PF 477736, PF 00477736, Src, Yes, RET
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
97.58% (May vary between batches)
Solubility
DMSO:50 mg/mL (119.2 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.77 mM)
Smiles
Cn1cc (cn1) -c1[nH]c2cc (NC (=O) [C@H] (N) C3CCCCC3) cc3c2c1cn[nH]c3=O
Molecular Formula
C22H25N7O2
Molecular Weight
419.48
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19219774-01PF-06821497
GTR19218762-01PF-07284892
GTR19217007-01PF-04745637
GTR19216918-01PF-04885614
GTR19213808-01PF-03463275
GTR19212469-01PF-07054894
GTR19212080-01PF-184
GTR19210491-01PF-07258669
GTR19208369-01PF-04671536
GTR19208220-01PF-05150122

Alternative Products

CatalogName
B1437-10PF-477736
T6028-01PF 477736

Popular Products