PF 477736

• Target:

  VEGFR|||c-RET|||Chk|||FGFR|||FLT|||Aurora Kinase|||c-Fms|||CDK|||Src

• Related Pathways:

  Cell Cycle/Checkpoint|||Apoptosis|||Chromatin/Epigenetic|||Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity:

  0.9994

• Bioactivity:

  PF 477736 (PF-736, PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.

• Smiles:

  Cn1cc(cn1)-c1[nH]c2cc(NC(=O)[C@H](N)C3CCCCC3)cc3c2c1cn[nH]c3=O

• Molecular Formula:

  C22H25N7O2

• Molecular Weight:

  419.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  952021-60-2