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ML221

CAT: 0931-T4390-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T4390-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
877636-42-5
Target
Arrestin, Apelin receptor
Related Pathways
GPCR/G Protein
Purity
0.9774
Bioactivity
ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.
Smiles
[O-][N+](=O)c1ccc(cc1)C(=O)Oc1coc(CSc2ncccn2)cc1=O
Molecular Formula
C17H11N3O6S
Molecular Weight
385.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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S8695-01ML221
A19446-10ML221 10mg
A19446-5ML221 5mg
A19446-50ML221 50mg
A19446-100ML221 100mg
A19446-25ML221 25mg
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