Products for Research Use Only

EMD638683

CAT: 0013-GTR19169741-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169741-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EMD638683 is a potent and selective serum- and glucocorticoid-regulated kinase (SGK) inhibitor with an IC50 of 3 μM. This small molecule is a valuable research tool for investigating SGK1's role in hypertension, renal function, and cellular ion transport in both in vitro and in vivo models.
CAS Number
1181770-72-8
Product Name Alternative
Inhibitor, EMD638683, EMD-638683, EMD 638683, inhibit, SGK1, SGK, Serum and glucocorticoid-regulated kinase, Serum-glucocorticoid regulated kinase
Field of Research
Metabolism Research
Purity
95.47% (May vary between batches)
Solubility
DMSO:50 mg/mL (137.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.49 mM)
Smiles
CCc1c (C) c (O) ccc1C (=O) NNC (=O) C (O) c1cc (F) cc (F) c1
Molecular Formula
C18H18F2N2O4
Molecular Weight
364.34
References & Citations
Sheyda Bahiraii er al. Role of Inositol Hexakisphosphate Kinases in Vascular Smooth Muscle Cell Calcification International Journal of Molecular Sciences, (2026)
Storage Conditions
-20°C
Notes
For research use only.