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GSK467

CAT: 0013-GTR19169690-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169690-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK467 is a potent and selective KDM5/JARID1 histone demethylase inhibitor with a Ki of 10 nM. This compound is a valuable research tool for studying epigenetic regulation in cancer and development, applicable in both cellular and biochemical assays.
CAS Number
1628332-52-4
Product Name Alternative
GSK467, GSK-467, GSK 467, HistoneMethyltransferase, Histone Demethylase, Histone Methyltransferase, HistoneDemethylase, HCC, Inhibitor, human multiple myeloma tumor, PLU1, inhibit, JARID1B, JARID1A, anticancer
Field of Research
Epigenetics & Chromatin
Purity
99.55% (May vary between batches)
Solubility
DMSO:20.83 mg/mL (65.23 mM)
Smiles
O=c1[nH]c (Oc2cnn (Cc3ccccc3) c2) nc2cnccc12
Molecular Formula
C17H13N5O2
Molecular Weight
319.32
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-((1-Benzyl-1H-pyrazol-4-yl)oxy)pyrido[3,4-d]pyrimidin-4(3H)-one
CAS Number1628332-52-4
PubChem CID135567128
IUPAC Name2-(1-benzylpyrazol-4-yl)oxy-3H-pyrido[3,4-d]pyrimidin-4-one
Molecular FormulaC17H13N5O2
Molecular Weight319.32
XLogP1.5
Topological Polar Surface Area81.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count24
Formal Charge0
Complexity491
SMILES
C1=CC=C(C=C1)CN2C=C(C=N2)OC3=NC4=C(C=CN=C4)C(=O)N3
InChI
InChI=1S/C17H13N5O2/c23-16-14-6-7-18-9-15(14)20-17(21-16)24-13-8-19-22(11-13)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H,20,21,23)
InChIKey
ZTYRLXUTLYBVHH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-((1-Benzyl-1H-pyrazol-4-yl)oxy)pyrido[3,4-d]pyrimidin-4(3H)-one
CAS: 1628332-52-4
CID: 135567128
Formula: C17H13N5O2
MW: 319.32
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight319.32
XLogP31.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass319.10692467
Monoisotopic Mass319.10692467
Topological Polar Surface Area81.4 Ų
Heavy Atom Count24
Formal Charge0
Complexity491
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
DQC33252-01GSK467
A18807-100GSK467 100mg
A18807-50GSK467 50mg
A18807-10GSK467 10mg
A18807-25GSK467 25mg
A18807-1GSK467 1mg
A18807-5GSK467 5mg
A18807-10mM-DGSK467 10mM * 1mL in DMSO

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