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PITSTOP2

CAT: 0013-GTR19166881-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166881-01Size:5 mg
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Description
Clathrin-IN-1 is a small molecule inhibitor that targets the terminal domain of clathrin to block clathrin-mediated endocytosis (CME) . It serves as a valuable research tool for investigating endocytic pathways and has shown potential in anti-cancer studies, including in vitro cellular research.
CAS Number
1332879-52-3
Product Name Alternative
Domain, Clathrin-IN-1, clathrin, amphiphysin, Human immunodeficiency virus, HIV Protease, HIV, HIVProtease, endocytosis, Inhibitor, inhibit, terminal, vesicle, synaptic, Pitstop2
Field of Research
Cell Biology
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to at least 30 mg/ml)
Smiles
S (NC=1SC (=CC2=CC=C (Br) C=C2) C (=O) N1) (=O) (=O) C=3C4=C (C=CC3) C=CC=C4
Molecular Formula
C20H13BrN2O3S2
Molecular Weight
473.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[ (5Z) -5-[ (4-Bromophenyl) methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]naphthalene-1-sulfonamide

Chemical Information

Pitstop2
CAS Number1332879-52-3
PubChem CID136227331
IUPAC Name(NE)-N-[(5Z)-5-[(4-bromophenyl)methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]naphthalene-1-sulfonamide
Molecular FormulaC20H13BrN2O3S2
Molecular Weight473.4
XLogP5.5
Topological Polar Surface Area109
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count28
Formal Charge0
Complexity767
SMILES
C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)/N=C/3\NC(=O)/C(=C/C4=CC=C(C=C4)Br)/S3
InChI
InChI=1S/C20H13BrN2O3S2/c21-15-10-8-13(9-11-15)12-17-19(24)22-20(27-17)23-28(25,26)18-7-3-5-14-4-1-2-6-16(14)18/h1-12H,(H,22,23,24)/b17-12-
InChIKey
CGDLWHGPJPVPDU-ATVHPVEESA-N
Chemical Structure
2D Structure
2D structure of Pitstop2
CAS: 1332879-52-3
CID: 136227331
Formula: C20H13BrN2O3S2
MW: 473.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight473.4
XLogP35.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass471.95510
Monoisotopic Mass471.95510
Topological Polar Surface Area109 Ų
Heavy Atom Count28
Formal Charge0
Complexity767
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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