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PITSTOP2

CAT: 0498-bs-82818C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82818C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PITSTOP2 inhibits clathrin-mediated endocytosis via blockade of endocytic ligand association with the clathrin terminal domain leading to clathrin coat assembly inhibition.1 It was able to cause a collapse of the nucleocytoplasmic permeability barrier and a reduction of Importin-ß binding.2 PITSTOP2 reduced viability in HeLa cells by trapping dividing cells in metaphase through loss of mitotic spindle integrity.3
Conjugation
Unconjugated
Buffer
Pink solid
Storage Conditions
-20°C

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