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RO-0335

CAT: 0013-GTR19165696-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19165696-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RO-0335 is a potent diphenylether NNRTI with sub-nanomolar activity against wild-type HIV-1 (IC50 = 1.1 nM) . It demonstrates broad efficacy, maintaining activity (IC50 < 100 nM) against 92% of NNRTI-resistant clinical isolates in virological assays, supporting its use in antiretroviral resistance research.
CAS Number
867365-76-2
Product Name Alternative
Inhibitor, HIV-1, inhibit, novel, nonnucleoside, diphenylether, potent, RO 0335, RO0335, RO-0335, Ro-0335, ReverseTranscriptase, Reverse Transcriptase
Field of Research
Infectious Disease & Virology
Purity
98.90% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.72 mM) ; DMSO:200 mg/mL (348.91 mM)
Smiles
NS (=O) (=O) c1ccc (NC (=O) Cc2ccc (Br) c (Oc3cc (Cl) cc (c3) C#N) c2F) c (Cl) c1
Molecular Formula
C21H13BrCl2FN3O4S
Molecular Weight
573.22
Storage Conditions
-20°C
Notes
For research use only.

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