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Antibacterial agent 227

CAT: 0804-HY-161797Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161797Size:1 Each
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Description
Antibacterial agent 227 (Compd 29) is a SerRS (Seryl-tRNA synthetase) inhibitor. Antibacterial agent 227 has a significant inhibitory effect on the growth of planktonic and biofilm culture of Staphylococcus aureus 25923 with MIC (minimum inhibitory concentration) value of 32 µg/ml. Antibacterial agent 227 can be proposed as effective antiseptic toward multidrug-resistant biofilm-forming S. aureus isolates[1].
CAS Number
301304-67-6
UNSPSC
12352005
Target
Aminoacyl-tRNA Synthetase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-227.html
Smiles
O=C(N1)C(C)=NN=C1N/N=C/C2=C(O)C(OC)=CC=C2
Molecular Formula
C12H13N5O3
Molecular Weight
275.26
References & Citations
[1]Volynets GP, et al. Identification of novel antistaphylococcal hit compounds. J Antibiot (Tokyo) . 2024 Jun 25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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