Products for Research Use Only
RegisterLogin

MK-4827 hydrochloride

CAT: 0013-GTR19164004-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19164004-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A highly potent PARP inhibitor with IC50 of 3.8 nM/2.1 nM for PARP1/PARP2; inhibits PARP activity with EC50=4 nM in a whole cell assay, and inhibits proliferation of cancer cells with mutant BRCA-1 and BRCA-2 with CC50 in the 10 100 nM range; well tolerated in vivo and demonstrates efficacy as a single agent in a xenograft model of BRCA-1 deficient cancer.Ovarian Cancer Approved.
CAS Number
1038915-64-8
Product Name Alternative
Niraparib hydrochloride | MK 4827 hydrochloride | MK4827 hydrochloride
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
C1CC (CNC1) C2=CC=C (C=C2) N3C=C4C=CC=C (C4=N3) C (=O) N.Cl
Molecular Formula
C19H21ClN4O
Molecular Weight
356.8492
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2H-Indazole-7-carboxamide, 2-[4- (3S) -3-piperidinylphenyl]-, hydrochloride (1:1)

Related Products

CatalogName
GTR19164005-01MK-4827
GTR19173994-01MK-4827 Racemate
GTR19164003-01MK-4827 tosylate
GTR19173995-01MK 212 hydrochloride
GTR19211137-01MK-0736 hydrochloride
GTR19210917-01MK 761 hydrochloride
GTR19205384-01MK-8033 hydrochloride
GTR19239357-01MK-3207 Hydrochloride
GTR19242498-01MK-8998 hydrochloride
GTR19242509-01MK-825 hydrochloride hemi-ethylacetate

Alternative Products

CatalogName
B1163-10MK-4827 hydrochloride
T12068-01MK-8033 hydrochloride
MBS5757462MK 212 hydrochloride
MBS5811367MK-0736 hydrochloride
HNB11620-01MK-3207 Hydrochloride
HY-118930A-01MK-0493 (hydrochloride)
MBS3606830-01MK-3207 (Hydrochloride)
MBS3603053MK-8353 hydrochloride
HY-112290AMK-0736 (hydrochloride)
T69018-01MK 761 hydrochloride

Popular Products