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Oxaprozin

CAT: 0013-GTR19162782-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162782-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oxaprozin is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID) used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. (In Vitro) :Oxaprozin induces apoptosis in a dose-dependent manner. Oxaprozin increases caspase-3 activity in the activated but not in the resting condition. NF-κB activation is inhibited by Oxaprozin (50 μM) . Oxaprozin inhibits activation of the IKK system induced by the reagent IκBα.Oxaprozin (100 μM) induces the strongest proapoptotic effect and significantly increases CD40L-treated monocyte apoptosis. Oxaprozin treatment inhibits CD40L-induced Akt and NF-κB (p65) phosphorylation.
CAS Number
21256-18-8
Product Name Alternative
Daypro | NSC 310839 | Wy 21743
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 27 mg/mL (92.04 mM) ; DMSO: 59 mg/mL (201.14 mM)
Smiles
CC1COC2=C3N1C=C (C (O) =O) C (C3=CC (F) =C2N4CCN (C) CC4) =O
Molecular Formula
C18H15NO3
Molecular Weight
293.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
9-fluoro-3-methyl-10- (4-methylpiperazin-1-yl) -7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

Alternative Products

CatalogName
018865Oxaprozin
HY-B0808S1-01Oxaprozin-d5

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