Products for Research Use Only
RegisterLogin

Stavudine

CAT: 0013-GTR19162654-01Size: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19162654-01Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Stavudine is a nucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. (In Vitro) :Stavudine (d4T) (50 μM) significantly reduces the expression of the NLRP3 inflammasome gene, IL-18 production and Aβ 42-stimulated cellular production of IL-1β in THP-1 derived macrophages.Stavudine (d4T) (50 μM) inhibits the assembly of the NLRP3 inflammasome complex and down-regulates the phagocytosis of Aβ 42 by macrophages.Stavudine (d4T) (10 μM, 7 or 14 days) significantly induced CEM cells apoptosis, especially after 14 days, and increases hydrogen peroxide levels. (In Vivo) :Stavudine (d4T) (500 mg/kg, daily liquid, 2 weeks) can rapidly induce fat depletion and mild liver damage at high dose in male RjOrl Swiss mice.
CAS Number
3056-17-5
Product Name Alternative
D4T | NSC 163661
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 15 mg/mL (66.9 mM) ; DMSO: 45 mg/mL (200.7 mM)
Smiles
OC[C@@H]1C=C[C@H] (N2C (NC (C (C) =C2) =O) =O) O1
Molecular Formula
C10H12N2O4
Molecular Weight
224.21
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- ((2R,5S) -5- (hydroxymethyl) -2,5-dihydrofuran-2-yl) -5-methylpyrimidine-2,4 (1H,3H) -dione

Alternative Products

CatalogName
HY-B0116-01Stavudine
JDA41490-01α-Stavudine
RM-S200105-01Stavudine EP Impurity E (α-Stavudine)
B2225-5.1Stavudine (d4T)
JFA62473Stavudine sodium
HY-B0116R-01Stavudine (Standard)
HY-B0116S-01Stavudine-d4
HY-B0116AStavudine (sodium)
TRC-S685245-500MGalpha-Stavudine

Popular Products