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VS-5584

CAT: 0013-GTR19160924-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160924-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VS-5584, also known as SB2343, is a potent and selective inhibitor of both phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinase in the PI3K/mTOR signaling pathway, with potential antineoplastic activity. PI3K/mTOR kinase inhibitor VS-5584 inhibits mTOR kinase and all class I PI3K isoforms. Consequently, this disrupts phosphorylation of substrates downstream of PI3K and mTOR and may result in apoptosis and growth inhibition in susceptible tumor cells. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy.
CAS Number
1246560-33-7
Product Name Alternative
VS5584 | VS 5584 | VS5584 | SB2343
Purity
>98% (HPLC)
Solubility
DMSO : 33.33 mg/mL. 94.04 mM
Smiles
CC (C) n1c (C) nc2c1nc (nc2c1cnc (N) nc1) N1CCOCC1
Molecular Formula
C17H22N8O
Molecular Weight
354.41
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
5- (9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl) pyrimidin-2-amine

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