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24 (S) -hydroxycholesterol

CAT: 0013-GTR19154310-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19154310-01Size:1 mg
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Description
24 (S) -hydroxycholesterol
CAS Number
474-73-7
Product Name Alternative
Cerebrosterol
Field of Research
Cell Biology, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
LXR agonist, endogenous cholesterol metabolite
Form
Powder
Solubility
Soluble in DMSO (up to 10 mg/ml with warming) or in Ethanol (up to 10 mg/ml) .
Molecular Formula
C27H46O2
Molecular Weight
402.7
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
Cholest-5-ene-3β,24S-diol

Chemical Information

24(S)-Hydroxycholesterol

(24S)-24-hydroxycholesterol is a 24-hydroxycholesterol that has S configuration at position 24. It is the major metabolic breakdown product of cholesterol in the brain. It has a role as a biomarker, a mouse metabolite and a human blood serum metabolite.

CAS Number474-73-7
PubChem CID121948
IUPAC Name(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Molecular FormulaC27H46O2
Molecular Weight402.7
XLogP7
Topological Polar Surface Area40.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Heavy Atom Count29
Formal Charge0
Complexity624
SMILES
C[C@H](CC[C@@H](C(C)C)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
InChI
InChI=1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1
InChIKey
IOWMKBFJCNLRTC-XWXSNNQWSA-N
Chemical Structure
2D Structure
2D structure of 24(S)-Hydroxycholesterol
CAS: 474-73-7
CID: 121948
Formula: C27H46O2
MW: 402.7
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight402.7
XLogP37
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass402.349780706
Monoisotopic Mass402.349780706
Topological Polar Surface Area40.5 Ų
Heavy Atom Count29
Formal Charge0
Complexity624
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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