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POMT2 rabbit pAb

CAT: 0855-ES14020-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES14020-01Size:50 µL
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Background
The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) .[provided by RefSeq, Oct 2008]
Description
The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS). [provided by RefSeq, Oct 2008],
UniProt
Q9UKY4
Swiss Prot
Q9UKY4
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human POMT2 AA range: 177-227
Target
POMT2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Gene ID (Human)
29954

UniProtKB · Q9UKY4

Protein O-mannosyl-transferase 2

POMT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UKY4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POMT2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.4.1.109
Processing
—
Secondary accessions
Q9NSG6, Q9P1W0, Q9P1W2
Protein keywords

Coding sequence diversity

Alternative splicing

Disease

Congenital muscular dystrophyDisease variantDystroglycanopathyLimb-girdle muscular dystrophyLissencephaly

Cellular component

Endoplasmic reticulumMembrane

PTM

GlycoproteinPhosphoprotein

Molecular function

GlycosyltransferaseTransferase

Ligand

Metal-binding

Technical term

Proteomics identificationReference proteome

Domain

RepeatTransmembraneTransmembrane helix