PI3Kδ-IN-16

• UNSPSC Description:

  PI3Kδ-IN-16 is a potent and selective inhibitor of PI3Kδ. PI3Kδ-IN-16 has a strong anti-proliferative effect on cells, causing cell cycle arrest and inducing apoptosis[1].

• Target Antigen:

  Apoptosis; PI3K

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pi3kδ-in-16.html

• Solubility:

  DMSO : 76.92 mg/mL (ultrasonic;adjust pH to 7 with 1 M HCL)

• Smiles:

  COC1=NC=C(C2=CC3=C(N=CN=C3N[C@@H](C)C(N4CCN(C)CC4)=O)C=C2)C=C1

• Molecular Weight:

  406.48

• References & Citations:

  [1]Lei H, et al. Discovery of potent and selective PI3Kδ inhibitors bearing amino acid fragments. Bioorg Chem. 2023 Sep;138:106594.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2766437-35-6