Lenalidomide-4-aminomethyl (hydrochloride)
CAT:
804-HY-138882A-03
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Lenalidomide-4-aminomethyl (hydrochloride)
- CAS Number: 444289-05-8
- UNSPSC Description: Lenalidomide-4-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1]
- Target Antigen: Ligands for E3 Ligase
- Type: Reference compound
- Related Pathways: PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/lenalidomide-4-aminomethyl-hydrochloride.html
- Smiles: O=C(C(N(CC1=C2C=CC=C1CN)C2=O)CC3)NC3=O.[H]Cl
- Molecular Weight: 309.75
- References & Citations: [1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
- Shipping Conditions: Room temperature