PEPC rabbit pAb

CAT: 0855-ES20649-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES20649-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Description
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],
Product Name Alternative
PGC; Gastricsin; Pepsinogen C
Reactivity
Plants
Immunogen
Synthetic Peptide of PEPC
Target
PEPC
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Dilution
WB: 1:2000-5000
Buffer
-20°C/1 year
Molecular Weight
105-109kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
105-109kD
Fragment
IgG
Subcellular Location
Extracellular space, extracellular exosome
Other Product Names
PGC; Gastricsin; Pepsinogen C

Related Products

CatalogName
EA149-01PEPC (Phospho Ser15) Rabbit pAb
ES20563-01PEPC (Phospho Ser15) rabbit pAb
ES8175-01PEPC Rabbit Polyclonal Antibody
ES8176-01PEPC (Phospho Ser15) Rabbit Polyclonal Antibody
ES19172-01PEPD rabbit pAb
ES3966-01PEPCK-C rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb
ES20826-01ATG5 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb

Alternative Products

CatalogName
E2350117PEPC Rabbit pAb
MBS8504863-01PEPC Rabbit Polyclonal Antibody
MBS8541998-01PEPC (Phospho-Ser15) Rabbit pAb
GB11966-50Anti-PCK1/PEPC Rabbit pAb
E12-320PEPC (Phospho Ser15) Rabbit Polyclonal Antibody
RA20329-01PEPC(Phospho Ser15) Rabbit Polyclonal Antibody
327874-01PEPC
347456-01PEPC discontinued
C47464-01PEPC Antibody
MBS1233741Recombinant Subtilisin-like serine protease pepC (pepC)

Popular Products