PEPCK-C rabbit pAb

CAT:

855-ES3966-01

Size:

50 μL

Price:

Ask

For price, please contact [email protected]

Description: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008],
Synonyms: PCK1; PEPCK1; Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; PEPCK-C; Phosphoenolpyruvate carboxylase
Gene ID: 5105
UniProt: P35558
Cellular Locus: Cytoplasm, cytosol. Endoplasmic reticulum. Phosphorylation at Ser-90 promotes translocation to the endoplasmic reticulum..
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PCK1. AA range:491-540
Clonality: Polyclonal
Validated Applications: WB, IHC, IF, ELISA
Stability: 1 year
Concentration: 1 mg/mL
Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight: 65kD
Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.