PEPC (Phospho Ser15) rabbit pAb
CAT:
855-ES20563-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PEPC (Phospho Ser15) rabbit pAb
- Description: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],
- Synonyms: PGC; Gastricsin; Pepsinogen C
- Gene ID: 5225
- UniProt: P20142
- Cellular Locus: Secreted.
- Host: Rabbit
- Species Reactivity: Plants
- Immunogen: Synthetic Peptide of PEPC (Phospho Ser15)
- Clonality: Polyclonal
- Validated Applications: WB, ELISA, IHC
- Stability: 1 year
- Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
- Molecular Weight: 105-110kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.