[D-Trp7,9,10]-Substance P

[D-Trp7,9,10]-Substance P

• CAS Number: 89430-38-6
• UNSPSC Description: [D-Trp7,9,10]-Substance P is a substance P analogue. Substance P stimulates substance P receptors but also inhibits ion conductance through nicotinic acetylcholine receptors[1].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Endocrinology
• Assay Protocol: https://www.medchemexpress.com/d-trp7-9-10-substance-p.html
• Solubility: 10 mM in DMSO
• Smiles: C([C@H](C(N[C@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@@H](CCSC)C(N)=O)=O)=O)NC([C@@H](NC([C@@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC([C@@H](NC(=O)[C@H]5N(C([C@@H](NC(=O)[C@H]6N(C([C@H](CCCNC(=N)N)N)=O)CCC6)CCCCN)=O)CCC5)CCC(N)=O)=O)CCC(N)=O)=O)=O)CC7=CC=CC=C7)=O)C=8C=9C(NC8)=CC=CC9
• Molecular Weight: 1588.88
• References & Citations: [1]Eardley D, et al. Both substance P agonists and antagonists inhibit ion conductance through nicotinic acetylcholine receptors on PC12 cells. Eur J Pharmacol. 1985;114(1):101-104.|[2]Mukai H, et al. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J Biol Chem. 1992;267(23):16237-16243.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported