(KO Validated) CD33 Polyclonal Antibody

• Background :

  Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This Single-pass type I membrane protein contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD33/Siglec-3 induces apoptosis in acute myeloid leukemia (in vitro) . CD33/Siglec-3 can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when CD33 is expressed in a plasma membrane.

• Description :

  This is a (KO Validated) CD33 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CD33, SIGLEC-3, SIGLEC3, p67, CD33 molecule

• Gene ID :

  945

• Swiss Prot :

  P20138

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human CD33

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  16kDa

• Observed Molecular Weight :

  16KDa

• Host or Source :

  Rabbit

• Isotype :

  IgG