(KO Validated) CD33 Polyclonal Antibody

CAT: 0866-RD90333A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD90333A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This Single-pass type I membrane protein contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD33/Siglec-3 induces apoptosis in acute myeloid leukemia (in vitro) . CD33/Siglec-3 can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when CD33 is expressed in a plasma membrane.
Description
This is a (KO Validated) CD33 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CD33, SIGLEC-3, SIGLEC3, p67, CD33 molecule
Gene ID
945
Swiss Prot
P20138
Reactivity
Human
Immunogen
Recombinant fusion protein of human CD33
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
16kDa
Observed Molecular Weight
16KDa
Host or Source
Rabbit
Isotype
IgG

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