Recombinant PERK Monoclonal Antibody

• Background:

  The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

• Description:

  This is a Recombinant PERK Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DKFZp781H1925, E2AK3, EC 2.7.11.1, Eif2ak3, Eukaryotic translation initiation factor 2 alpha kinase 3, Eukaryotic translation initiation factor 2-alpha kinase 3, Heme regulated EIF2 alpha kinase, HRI, HsPEK, Pancreatic eIF2 alpha kinase, Pancreatic eIF2-alpha kinas

• Gene ID:

  9451

• Swiss Prot:

  Q9NZJ5

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human PERK

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  47kDa

• Observed Molecular Weight:

  54kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG