PERK Polyclonal Antibody

CAT: 0866-RD232546A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD232546A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR) -induced G1 growth arrest due to the loss of cyclin D1.
Description
This is a PERK Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
DKFZp781H1925, E2AK3, EC 2.7.11.1, Eif2ak3, Eukaryotic translation initiation factor 2 alpha kinase 3, Eukaryotic translation initiation factor 2-alpha kinase 3, Heme regulated EIF2 alpha kinase, HRI, HsPEK, Pancreatic eIF2 alpha kinase, Pancreatic eIF2-alpha kinas
Swiss Prot
Q9NZJ5
Reactivity
Human
Immunogen
Synthesized peptide derived from the N-terminal region of human PERK
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, IF, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol pH 7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
125 kDa
Observed Molecular Weight
125 kDa
Host or Source
Rabbit
Isotype
IgG

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