PERK Polyclonal Antibody

• Background:

  Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR) -induced G1 growth arrest due to the loss of cyclin D1.

• Description:

  This is a PERK Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DKFZp781H1925, E2AK3, EC 2.7.11.1, Eif2ak3, Eukaryotic translation initiation factor 2 alpha kinase 3, Eukaryotic translation initiation factor 2-alpha kinase 3, Heme regulated EIF2 alpha kinase, HRI, HsPEK, Pancreatic eIF2 alpha kinase, Pancreatic eIF2-alpha kinas

• Swiss Prot:

  Q9NZJ5

• Reactivity:

  Human

• Immunogen:

  Synthesized peptide derived from the N-terminal region of human PERK

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC-p, IF, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol pH 7.4.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  125 kDa

• Observed Molecular Weight:

  125 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG