Recombinant Prohibitin Monoclonal Antibody

• Background:

  Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .

• Description:

  This is a Recombinant Prohibitin Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Epididymis luminal protein 215, Epididymis secretory sperm binding protein Li 54e, HEL 215, HEL S 54e, PHB, PHB, PHB1, Prohibitin

• Gene ID:

  5245

• Swiss Prot:

  P35232

• Reactivity:

  Human, Rat

• Immunogen:

  A synthetic peptide of human Prohibitin

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC-P

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  57 kDa

• Observed Molecular Weight:

  57 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG