DDIT3/CHOP Polyclonal Antibody

CAT: 0866-RD90293A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD90293A-01Size:60 μL
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Background
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Description
This is a DDIT3/CHOP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153, DNA damage inducible transcript 3
Gene ID
1649
Swiss Prot
P35638
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human DDIT3/CHOP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
144kDa/183kDa/184kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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