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DDIT4 Polyclonal Antibody

CAT: 0866-RD75767A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD75767A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS) . REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness.
Description
This is a DDIT4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
DDIT4, DDIT4, Dig2, DNA damage inducible transcript 4, DNA damage inducible transcript 4 protein, DNA damage-inducible transcript 4 protein, FLJ20500, HIF 1 responsive protein RTP801, HIF 1 responsive RTP801, HIF-1 responsive protein RTP801, Protein regulated in de
Swiss Prot
Q9NX09
Accession Number
BC007714
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human DDIT4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.8 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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