(KO Validated) MSH2 Polyclonal Antibody

• Background:

  This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a (KO Validated) MSH2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2, mutS homolog 2

• Gene ID:

  4436

• Swiss Prot:

  P43246

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein of human MSH2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IP

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000, IP 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  35kDa/48kDa/51kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG