(KO Validated) CRMP2/DPYSL2 Polyclonal Antibody

• Background:

  This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Description:

  This is a (KO Validated) CRMP2/DPYSL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2

• Gene ID:

  1808

• Swiss Prot:

  Q16555

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human CRMP2/CRMP2/DPYSL2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  16kDa/37kDa/78kDa

• Observed Molecular Weight:

  78kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG