(KO Validated) Beclin 1 Polyclonal Antibody

• Background:

  This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

• Description:

  This is a (KO Validated) Beclin 1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  BECN1, ATG6, VPS30, beclin1, beclin-1

• Gene ID:

  8678

• Swiss Prot:

  Q14457

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human Beclin 1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:100, IF 1:50-1:200

• Buffer:

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  92kDa/93kDa/94kDa/96kDa/97kDa

• Observed Molecular Weight:

  120KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG