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CKAP5 Polyclonal Antibody

CAT: 0866-RD85163A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD85163A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.
Description
This is a CKAP5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CKAP5, CHTOG, MSPS, TOG, TOGp, ch-TOG
Gene ID
9793
Swiss Prot
Q14008
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CKAP5 (NP_001008938.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
218 kDa/225 kDa/226 kDa
Observed Molecular Weight
250 kDa
Host or Source
Rabbit
Isotype
IgG

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