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CKAP5 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP07981-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07981-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2| which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.
CAS Number
9007-83-4
Synonyms
CKAP5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human CKAP5
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
223520
Antibody Type
Primary antibody
Isotype
IgG