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HSD11B1 Polyclonal Antibody

CAT: 0866-RD82237A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82237A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) ) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
Description
This is a HSD11B1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HSD11B1,11-DH,11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1
Gene ID
3290
Swiss Prot
P28845
Reactivity
Mouse
Immunogen
Recombinant fusion protein of human HSD11B1 (NP_005516.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
32 kDa
Observed Molecular Weight
32 kDa
Host or Source
Rabbit
Isotype
IgG

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