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HSD17B1 Polyclonal Antibody

CAT: 0866-RD265790A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD265790A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP (H) over NAD (H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
Description
This is a HSD17B1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HSD17B1,17-beta-HSD,20-alpha-HSD, E2DH, EDH17B2, EDHB17, HSD17, SDR28C1
Gene ID
3292
Swiss Prot
P14061
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human HSD17B1 (NP_000404.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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