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HSD11B2 Polyclonal Antibody

CAT: 0866-RD76883A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD76883A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor.
Description
This is a HSD11B2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
11 beta HSD2,11 beta hydroxysteroid dehydrogenase type 2,11 DH2,11-beta-HSD2,11-beta-hydroxysteroid dehydrogenase type 2,11-DH2, AME, AME1, Corticosteroid 11 beta dehydrogenase isozyme 2, Corticosteroid 11-beta-dehydrogenase isozyme 2, DHI2, HSD11B2, HSD11K, HSD2
Swiss Prot
P80365
Accession Number
NP_000187
Reactivity
Human
Immunogen
Synthetic peptide of human HSD11B2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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