TXNIP Polyclonal Antibody
CAT:
866-RD79761A-02
Size:
60 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TXNIP Polyclonal Antibody
- Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
- Synonyms: THIF,VDUP1,HHCPA78,EST01027
- CAS Number: 9007-83-4
- Swiss Prot: Q9H3M7
- Accession Number: NP_006463
- Host: Rabbit
- Reactivity: Human,Mouse,Rat
- Immunogen: Synthetic peptide of human TXNIP
- Clonality: Polyclonal
- Isotype: IgG
- Conjugation: Unconjugated
- Applications: IHC,ELISA
- Purification: Affinity purification
- Concentration: 1.9 mg/mL
- Dilution: IHC 1:30-150, ELISA 1:2000-10000
- Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.