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TXNIP Polyclonal Antibody

CAT:
866-RD79761A-02
Size:
60 μL
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
TXNIP Polyclonal Antibody - image 1

TXNIP Polyclonal Antibody

  • Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
  • Synonyms: THIF,VDUP1,HHCPA78,EST01027
  • CAS Number: 9007-83-4
  • Swiss Prot: Q9H3M7
  • Accession Number: NP_006463
  • Host: Rabbit
  • Reactivity: Human,Mouse,Rat
  • Immunogen: Synthetic peptide of human TXNIP
  • Clonality: Polyclonal
  • Isotype: IgG
  • Conjugation: Unconjugated
  • Applications: IHC,ELISA
  • Purification: Affinity purification
  • Concentration: 1.9 mg/mL
  • Dilution: IHC 1:30-150, ELISA 1:2000-10000
  • Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
  • Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.