TXNIP Polyclonal Antibody

• Background:

  This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

• Synonyms:

  TXNIP,ARRDC6,EST01027,HHCPA78,THIF,VDUP1

• Gene ID:

  10628

• Swiss Prot:

  Q9H3M7

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  A synthetic peptide of human TXNIP

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Applications:

  WB,IF

• Purification:

  Affinity purification

• Concentration:

  1mg/mL

• Dilution:

  WB 1:200-1:2000,IF 1:50-1:200

• Buffer:

  PBS with 0.05% proclin300,50% glycerol,pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  43kDa

• Observed Molecular Weight:

  43kDa