(KO Validated) SEC61B Polyclonal Antibody

• Background :

  The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.

• Description :

  This is a (KO Validated) SEC61B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  SEC61B

• Gene ID :

  10952

• Swiss Prot :

  P60468

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human SEC61B (NP_006799.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000 IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  9 kDa

• Observed Molecular Weight :

  12 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG