CASR Polyclonal Antibody

CAT: 0866-RD218582A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD218582A-01Size:20 µL
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Background
CASR (Calcium Sensing Receptor) is a Protein Coding gene. Diseases associated with CASR include Hypocalcemia, Autosomal Dominant and Hyperparathyroidism, Neonatal. Among its related pathways are Proton Pump Inhibitor Pathway, Pharmacodynamics and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and protein kinase binding. An important paralog of this gene is GPRC6A.The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH) -producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Description
This is a CASR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Ca sensing receptor, Ca2+ sensing receptor 1, Ca2+ sensing receptor, Calcium sensing receptor, CAR, CaSR, CASR, EIG8, Extracellular calcium sensing receptor, Extracellular calcium sensing receptor [Precursor], Extracellular calcium-sensing receptor, FHH, FIH, GPRC2A, H
Swiss Prot
P41180
Accession Number
BC112236
Reactivity
Human
Immunogen
Fusion protein of human CASR
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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