CAST Polyclonal Antibody

• Background :

  The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

• Description :

  This is a CAST Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  BS 17, Calpain inhibitor, Calpastatin, Cast, Heart type calpastatin, ICAL, MGC9402, Sperm BS 17 component, Sperm BS-17 component

• Swiss Prot :

  P20810

• Accession Number :

  BC013579

• Reactivity :

  Human

• Immunogen :

  Recombinant protein of human CAST

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.7 mg/mL

• Dilution :

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  77 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG