BD-3 Beta Defensin-3 Mouse Recombinant Protein

• Description:

  Beta Defensin-3 Mouse Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 41 amino acids and having a molecular mass of 4.6kDa. The BD-3 is purified by proprietary chromatographic techniques.

• Synonyms:

  Beta-defensin 3; BD-3; mBD-3; Defensin beta 3; Defb3; Bd3; MGC129397

• Gene Name:

  DEFB3

• UniProt:

  Q9WTL0

• Reactivity:

  Mouse

• Tissue Specificity:

  Highest expression in salivary glands, epididymis, ovary and pancreas and to a lesser extent in lung, liver and brain. Low or no expression in skeletal muscle and tongue.

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 98.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

• Bioactivity:

  50

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized Beta Defensin-3 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Antimicrobial activity against Gram-negative bacteria E.coli and P.aeruginosa.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized Beta Defensin-3 Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD-3 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

• Other Gene Names:

  Beta-defensin 3

• Subcellular Location:

  Secreted.