BD-4 Beta Defensin-4 Human Recombinant Protein

• Description:

  Beta Defensin-4 Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 50 amino acids and having a molecular mass of 6 kDa. The BD-4 is purified by proprietary chromatographic techniques.

• Synonyms:

  HBD-4; DEFB-4; HBD4; DEFB104B; Beta-defensin 4; BD-4

• Gene Name:

  DEFB104ADEFB104B

• UniProt:

  Q8WTQ1

• Reactivity:

  Human

• Tissue Specificity:

  High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested.

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 98.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

• Bioactivity:

  Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-50 ng/ml, corresponding to a specific activity of 20,000-10,000,000 units/mg.

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized Beta Defensin-4 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized Beta Defensin-4 Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD-3 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

• Other Gene Names:

  Beta-defensin 104

• Subcellular Location:

  Secreted.