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GSK8573

CAT: 0804-HY-107477-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-107477-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK8573 is an inactive control compound for GSK2801 (acetyl-lysine competitive inhibitor of BAZ2A and BAZ2B bromodomains) . GSK8573 has binding activity to BRD9 with a Kd value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy. GSK8573 can be used as a structurally related negative control compound in biological experiments[1].
CAS Number
1693766-04-9
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gsk8573.html
Concentration
10mM
Purity
99.53
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC(C1=CC(C2=CC=CC(OC)=C2)=C3C=C(OCCC)C=CN13)=O
Molecular Formula
C20H21NO3
Molecular Weight
323.39
Precautions
H315, H319
References & Citations
[1]Chen P, et al. Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B. J Med Chem. 2016 Feb 25;59 (4) :1410-24.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD9

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