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IDI1 rabbit pAb

CAT: 0855-ES15535-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES15535-01Size:50 µL
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Background
IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008]
Description
IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008],
UniProt
Q13907
Swiss Prot
Q13907
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human IDI1 AA range: 103-153
Target
IDI1
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Peroxisome .
Gene ID (Human)
3422

UniProtKB · Q13907

Isopentenyl-diphosphate Delta-isomerase 1

IDI1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13907
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IDI1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
5.3.3.2
Processing
—
Secondary accessions
B4E155, Q32Q13, Q53GQ6, Q86U81, Q8WUX8, Q96IZ4, Q9BQ74
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Acetylation

Coding sequence diversity

Alternative splicing

Biological process

Cholesterol biosynthesisCholesterol metabolismIsoprene biosynthesisLipid biosynthesisLipid metabolismSteroid biosynthesisSteroid metabolismSterol biosynthesisSterol metabolism

Molecular function

Isomerase

Ligand

MagnesiumMetal-binding

Cellular component

Peroxisome