Products for Research Use Only
RegisterLogin

Anti-Transcription factor E2F3 E2F3 Antibody

CAT: 0519-A03068-1Size: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0519-A03068-1Size:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The E2F transcription factor 3 (E2F3) is a member of a small family of transcription factors that function through binding of DP interaction partner proteins. E2F3 recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle (1) . Like the related E2F1 and E2F2, E2F3 is essential for cellular proliferation and progression through the cell cycle (2) . Altered copy number and activity of this gene have been observed in a number of human cancers (3) .
Description
Boster Bio Anti-Transcription factor E2F3 E2F3 Antibody (Catalog # A03068-1) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Synonyms
E2F transcription factor 3, E2F-3
Gene Name
E2F3
UniProt
O00716
Host
Rabbit
Reactivity
Human, Mouse
Cross Reactivity
E2F3 antibody is human and mouse reactive. At least three isoforms of E2F3 are known to exist; this antibody will detect only the largest isoform. This antibody is predicted to not cross-react with other members of the E2F transcription factor family.
Immunogen
E2F3 antibody was raised against a 15 amino acid peptide near the center of human E2F3. The immunogen is located within amino acids 150 - 200 of E2F3.
Clonality
Polyclonal
Applications
ELISA, WB, IHC-P, IF
Field of Research
Cancer, Cell Cycle
Purification
E2F3 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity) .
Molecular Weight
49162 MW
Shipping Conditions
Available
Storage Conditions
E2F3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Fragment
IgG
Other Gene Names
E2F transcription factor 3
Subcellular Location
Nucleus.
Protein Name
E2F transcription factor 3

Related Products

CatalogName
A05062Anti-Transcription factor E2F6 E2F6 Antibody
A02322Anti-Transcription factor E2F8 E2F8 Antibody
A04195Anti-Transcription factor E2F7 E2F7 Antibody
A00257-1Anti-Transcription factor E2F1 E2F1 Antibody
PA2156Anti-Transcription factor E2F4 E2F4 Antibody Picoband®
PA1811Anti-Transcription factor E2F6 E2F6 Antibody Picoband®
PA1810Anti-Transcription factor E2F2 E2F2 Antibody Picoband®
PA1560Anti-Transcription factor E2F1 E2F1 Antibody Picoband®
A03068-3Anti-E2F3 Antibody Picoband®
A03068Anti-E2F3 Antibody Picoband®

Alternative Products

CatalogName
abx376734-01Transcription Factor E2F3 (E2F3) Antibody
034889E2F3, ID (E2F3, KIAA0075, Transcription factor E2F3)
MBS6294094-01E2F3, ID (E2F3, KIAA0075, Transcription factor E2F3) (APC)
MBS6294093-01E2F3, ID (E2F3, KIAA0075, Transcription factor E2F3) (AP)
MBS6294103-01E2F3, ID (E2F3, KIAA0075, Transcription factor E2F3) (PE)
abx315234-01Transcription Factor E2F3 (E2F3) Antibody (HRP)
abx315235-01Transcription Factor E2F3 (E2F3) Antibody (FITC)
370956E2F3, CT (Transcription Factor E2F3)
abx315236-01Transcription Factor E2F3 (E2F3) Antibody (Biotin)
MBS6294096-01E2F3, ID (E2F3, KIAA0075, Transcription factor E2F3) (FITC)

Popular Products