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SAH-SOS1A

CAT: 0013-GTR19029118Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19029118Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This small molecule inhibitor disrupts the KRas-SOS1 interaction by binding the KRas nucleotide pocket (Kd 106-176 nM), blocking nucleotide exchange and downstream ERK-MAPK signaling. It exhibits cell permeability and cytotoxicity in KRas-driven cancer models, supporting its use in oncology research for both in vitro and in vivo studies of Ras pathway dysregulation.
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Molecular Weight
2187.53
Storage Conditions
-20°C
Notes
For research use only.

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